Forget Me Not- MOTS-c Peptide

• Treatment for Cognitive Disorders
• Treatment for Dementia
• Improved Muscle Tone
• Reduction in Bodyfat
• Weight Management
• Treatment for Early Onset Heart Disease

Dosing Instructions:

Each 2fl oz bottle contains 600 sprays

Small Pets (Under 20#’s)- 5 sprays on food 2-3 times per day

Medium Pets (20-50#’s)-10 sprays on food 2-3 times per day

Large Pets (50#’s and Up)-15 sprays on food 2-3 times per day

PetTides

Forget Me Not- MOTS c

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c), a mitochondrial-derived peptide, has garnered attention for its potential therapeutic benefits, including its role in aging, metabolism, and cellular stress responses. Recent research suggests that MOTS-c might also play a significant role in the prevention and treatment of neurodegenerative diseases like Alzheimer’s and dementia. Here’s a detailed description of how MOTS-c can help in these contexts for pets:

 Mechanism of Action
MOTS-c functions by modulating various cellular pathways that are crucial for maintaining cellular health and resilience against stress. Key mechanisms include:
- **Mitochondrial Protection**: Enhances mitochondrial function and biogenesis, which is critical for energy production and cellular health.
- **Antioxidant Effects**: Reduces oxidative stress, a significant factor in neurodegeneration.
- **Anti-Inflammatory Properties**: Decreases chronic inflammation, which is linked to the progression of Alzheimer’s and dementia.
- **Metabolic Regulation**: Improves insulin sensitivity and glucose metabolism, which can impact brain health.

### Benefits in the Prevention and Treatment of Alzheimer’s and Dementia in Pets
1. **Mitochondrial Health and Function**:
- **Enhanced Energy Production**: By improving mitochondrial function, MOTS-c ensures that neurons and other brain cells receive adequate energy, which is essential for their proper functioning and survival.
- **Mitochondrial Biogenesis**: Promotes the formation of new mitochondria, which can replace damaged ones and support cellular health.

2. **Reduction of Oxidative Stress**:
- **Antioxidant Activity**: MOTS-c helps in reducing the accumulation of reactive oxygen species (ROS) in the brain, protecting neurons from oxidative damage.
- **Neuroprotection**: By mitigating oxidative stress, MOTS-c protects neurons from damage and death, which is crucial in preventing cognitive decline.

3. **Anti-Inflammatory Effects**:
- **Reduction of Neuroinflammation**: Chronic inflammation in the brain is a hallmark of Alzheimer’s and dementia. MOTS-c can reduce this inflammation, protecting brain cells from inflammatory damage.
- **Cytokine Modulation**: It helps in modulating the levels of inflammatory cytokines, reducing the overall inflammatory response in the brain.

4. **Improvement of Insulin Sensitivity and Metabolic Health**:
- **Brain Insulin Sensitivity**: Impaired insulin signaling in the brain is associated with Alzheimer’s disease. MOTS-c improves insulin sensitivity, which can enhance neuronal function and survival.
- **Glucose Metabolism**: By improving glucose metabolism, MOTS-c ensures that brain cells have a steady supply of energy, which is vital for cognitive functions.

5. **Cognitive Function and Neurogenesis**:
- **Support for Neurogenesis**: MOTS-c can promote the growth of new neurons and synapses, which is essential for learning, memory, and overall cognitive function.
- **Cognitive Enhancement**: Through its various protective and supportive roles, MOTS-c can help in maintaining cognitive functions and slowing the progression of cognitive decline.

Conclusion
MOTS-c offers a promising avenue for the prevention and treatment of Alzheimer’s and dementia in pets. By enhancing mitochondrial function, reducing oxidative stress and inflammation, improving insulin sensitivity, and supporting neurogenesis, MOTS-c can help maintain cognitive function and slow the progression of neurodegenerative diseases.